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Melanotan 1 (MT1) is a high-purity research peptide (Afamelanotide analog) designed for advanced melanocortin receptor studies. Verified at 99.98% purity with batch-specific COA, this compound is widely utilized in MC1R signaling, melanogenesis, and photoprotection research models.

Technical Specifications: Melanotan 1 (MT1)

Peptide Melanotan 1 (MT1) / Afamelanotide
Sequence Length 13 Amino Acids
Formula C₇₈H₁₁₁N₂₁O₁₉
Mol. Weight 1,646.85 g/mol
CAS 75921-69-6
Purity 99.98% (HPLC Verified)
Testing HPLC / ESI-MS / COA Included
Amount 10mg per vial
Target MC1R (High Selectivity)
BBB Crossing Limited
Half-Life ~1–2 hours
Reconstitution Bacteriostatic or Sterile Water
Storage -20°C (Long-Term)
Stability 1–2 months (Aliquoted, -20°C)
Applications MC1R, Melanogenesis, Photoprotection
Dosage (In-Vitro) 10–1000 nM
Dosage (In-Vivo) 0.5–2 mg (Model Dependent)
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Description

The Original Melanocortin – Melanotan 1 (MT1) 10mg. Pure Pigmentation Research. Unmatched Purity.

Buy Melanotan 1 MT1 10mg Online Europe, You know the history. Melanotan 1 (MT1), also known as Afamelanotide, is the first-generation melanocortin peptide that revolutionized the study of pigmentation, melanogenesis, and UV protection. Unlike later analogs, MT1 is the clinically studied, reference standard for melanocortin-1 receptor (MC1R) research.

This is not a tanning compound. This is a precision research tool for the study of melanocyte biology, photoprotection, and melanocortin receptor signaling.  Buy Melanotan 1 MT1 10mg Online Europe

Introducing the Melanotan 1 (MT1) 10mg Peptide from buypurepeptideseu.com – the original, most researched melanocortin peptide available for European researchers. Ten milligrams of lyophilized, receptor-grade peptide for advanced pigmentation, photoprotection, and melanocyte research.

Whether you are in Berlin studying MC1R signaling pathways, in Paris researching UV-induced DNA damage protection, or in Milan investigating melanocyte biology, this peptide is your laboratory’s essential tool. We ship discreetly and securely to Albania, Andorra, Austria, Belgium, Bosnia, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Moldova, Monaco, Montenegro, Netherlands, North Macedonia, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Ukraine, Vatican City, and the United Kingdom.

When you need to buy peptides online Viennabuy peptides Brusselsbuy peptides online Milan, or figure out how can I buy peptides online Warsaw, we are your premium European supplier. And now, we offer the original melanocortin peptide for serious pigmentation research. Buy Melanotan 1 MT1 10mg Online Europe


What Is Melanotan 1 (MT1)? The Science of Melanocortin Research

Let us break down the pharmacology. Melanotan 1 (MT1), also known as Afamelanotide or [Nle4, D-Phe7]-α-MSH, is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH). It is a potent, selective agonist of the melanocortin-1 receptor (MC1R). Buy Melanotan 1 MT1 10mg Online Europe

Mechanism of action: MT1 binds to MC1R on melanocytes, activating the cyclic AMP (cAMP) signaling pathway. This leads to upregulation of tyrosinase and other melanogenic enzymes, increasing the production of eumelanin (dark, photoprotective pigment) rather than pheomelanin (light, UV-sensitive pigment). Buy Melanotan 1 MT1 10mg Online Europe

Key differences from Melanotan 2 (MT2):

  • MT1 is more selective for MC1R, with minimal activity at other melanocortin receptors (MC3R, MC4R)

  • MT1 does not cross the blood-brain barrier significantly, avoiding CNS effects

  • MT1 has no reported effects on appetite or libido (unlike MT2)

  • MT1 is the clinically approved version (Afamelanotide) for specific indications

Research applications: MT1 is the reference standard for studying MC1R signaling, melanogenesis, and photoprotection. It is used in research on:

  • Melanocyte biology and pigmentation

  • UV-induced DNA damage and protection

  • Skin cancer prevention models

  • Vitiligo and hypopigmentation disorders

  • Erythropoietic protoporphyria (EPP) research

The Pure Peptides Shop advantage: Our Melanotan 1 (MT1) 10mg Peptide is manufactured under GMP peptide manufacturer EU standards. Each batch is third party tested with a Certificate of Analysis (COA) verifying 99.98% purity. We do not cut corners. We do not hide our lab testing transparency.

This is analytical grade Melanotan 1 Europe in lyophilized format. For researchers who need the original, clinically studied melanocortin peptide, MT1 is the essential tool. Buy Melanotan 1 MT1 10mg Online Europe


Product Deep Dive: Melanotan 1 (MT1) 10mg Specifications

Peptide Name: Melanotan 1 (MT1), Afamelanotide, [Nle4, D-Phe7]-α-MSH
Full Name: [Nle4, D-Phe7]-alpha-Melanocyte Stimulating Hormone
Amino Acid Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ (13 amino acids)
Molecular Formula: C₇₈H₁₁₁N₂₁O₁₉
Molecular Weight: 1,646.85 g/mol
CAS Number: 75921-69-6 (Afamelanotide)
Purity Guarantee: 99.98% (HPLC verified, COA included)
Form: Lyophilized powder (white to off-white cake)
Reconstitution: Bacteriostatic water or sterile water (do not use DMSO or alkaline solutions)
Storage (Lyophilized): -20°C (-4°F) for long-term storage; stable for 3 months at 4°C
Storage (Reconstituted): Aliquot and store at -20°C (-4°F); avoid freeze-thaw cycles

Comparison: MT1 vs MT2

Parameter Melanotan 1 (MT1) Melanotan 2 (MT2)
Sequence Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH₂
Molecular Weight 1,646.85 g/mol 1,024.23 g/mol
MC1R Selectivity High (selective) Moderate (non-selective)
MC4R Activity Minimal Significant
Blood-Brain Barrier Limited crossing Crosses readily
CNS Effects None reported Appetite suppression, libido effects
Clinical Status Approved (Afamelanotide) Research only

Primary Research Applications:

  • MC1R receptor signaling and activation studies (cAMP pathway)

  • Melanogenesis and eumelanin synthesis research

  • UV-induced DNA damage and photoprotection studies

  • Skin cancer prevention and UV protection models

  • Vitiligo and hypopigmentation disorder research

  • Erythropoietic protoporphyria (EPP) research

  • Melanocyte biology and differentiation studies

  • Pigmentation disorder research

Mechanism of Action Summary:

Pathway Target Effect of MT1
MC1R Activation Melanocortin-1 receptor on melanocytes cAMP pathway activation
Tyrosinase Upregulation Melanogenic enzyme Increased melanin production
Eumelanin Synthesis Melanosome Dark, photoprotective pigment
UV Protection Melanocyte DNA Reduced UV-induced DNA damage
Antioxidant Response Melanocyte Increased melanocyte survival

Why European Researchers Choose Melanotan 1 (MT1)

You are a serious researcher studying pigmentation, photoprotection, or melanocortin signaling. You understand that MT1 is the clinically studied, reference standard for MC1R research. You need a peptide that is selective, pure, and reliable.

The problem with MT2 for MC1R research:

  • MT2 is non-selective, activating MC3R and MC4R in addition to MC1R

  • MT2 crosses the blood-brain barrier, causing CNS effects that confound research

  • MT2 has no clinical approvals; MT1 (Afamelanotide) is the approved standard

The MT1 advantage for research:

  • MC1R-selective: Minimal off-target receptor activation

  • No CNS effects: Does not significantly cross the blood-brain barrier

  • Clinically validated: MT1 (Afamelanotide) is the approved reference standard

  • Pure pigmentation research: No appetite or libido confounders

What makes MT1 unique for research:

  • Selective MC1R agonism: Cleaner pharmacology than MT2

  • Photoprotection studies: Gold standard for UV protection research

  • Melanocyte biology: Reference compound for melanogenesis studies

  • Vitiligo research: Clinically studied for repigmentation

Who uses our Melanotan 1 (MT1) 10mg Peptide?

  • MC1R signaling and melanocortin receptor research institutions

  • Pigmentation and melanocyte biology laboratories

  • Photoprotection and UV damage research centers

  • Skin cancer prevention and DNA damage studies

  • Vitiligo and hypopigmentation disorder research

  • Erythropoietic protoporphyria (EPP) research

  • Universities studying the original, clinically validated melanocortin peptide


The European Logistics Advantage (Why We Convert)

You are a professional researcher. You do not have time for customs delays or “where can I find a peptide shop in Albania” only to receive low-purity MT1. Our backend is designed for high-volume eCommerce and high-ticket researchers.

Speed: Orders placed before 14:00 CET ship same-day from our EU hub.

Discretion: Plain boxes. No “Melanotan” labels on outer packaging. Neutral customs declarations. Lyophilized vials are shipped with ice packs for stability.

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Trust Signals:

  • Secure payment via AES-256 encryption

  • Discreet delivery guaranteed

  • Third party tested peptides EU with COA included

  • ISO certified peptide supplier Europe standards

  • For research use only – full regulatory compliance

Urgency Trigger: Our Melanotan 1 (MT1) 10mg Peptide is manufactured in limited batches. Current stock for Central Europe is at 25% capacity. The next production run has a 6-8 week lead time. When it is gone, it is gone. Bulk deals available for institutional buyers.


FAQ: Your Questions- & Answered

1. Q: What is the difference between Melanotan 1 (MT1) and Melanotan 2 (MT2)?
A: MT1 is more selective for the MC1 receptor, does not significantly cross the blood-brain barrier, and has no reported CNS effects (appetite, libido). MT2 is non-selective, crosses the BBB, and affects MC3R and MC4R, causing appetite suppression and libido effects. MT1 (Afamelanotide) is the clinically approved version; MT2 is research-only.

2. Q: Is Melanotan 1 the same as Afamelanotide?
A: Yes. Melanotan 1 (MT1) is also known as Afamelanotide or [Nle4, D-Phe7]-α-MSH. Afamelanotide is the approved pharmaceutical name for MT1.

3. Q: What is the mechanism of action for MT1?
A: MT1 is a selective agonist of the melanocortin-1 receptor (MC1R) on melanocytes. Activation of MC1R stimulates the cAMP pathway, upregulating tyrosinase and other melanogenic enzymes, leading to increased production of eumelanin (dark, photoprotective pigment).

4. Q: How do I verify the 99.98% purity claim?
A: Every batch we ship has a unique Certificate of Analysis (COA) . You can scan the QR code on the box to see the HPLC chromatogram and mass spectrometry data. We are a third party tested peptides EU supplier with full lab testing transparency.

5. Q: Do you ship to my specific city (e.g., Vienna, Austria)?
A: Absolutely. We ship to buy peptides Viennabuy peptides Salzburgbuy peptides Grazbuy peptides Brusselsbuy peptides Amsterdambuy peptides Madridbuy peptides Barcelonabuy peptides Romebuy peptides Milanbuy peptides Naplesbuy peptides Munichbuy peptides Berlinbuy peptides Hamburgbuy peptides Frankfurtbuy peptides Parisbuy peptides Lyonbuy peptides Marseillebuy peptides Londonbuy peptides Manchesterbuy peptides Birmingham, and every major city in Europe.

6. Q: What is the difference between GMP and non-GMP peptides?
A: GMP peptide manufacturer EU standards are for pharmaceutical grade. Our MT1 is analytical grade (99.98%+), which exceeds many GMP standards for purity but is labeled “For Research Use Only” . This is GMP vs Non-GMP Peptides Explained.

7. Q: How should I reconstitute Melanotan 1?
A: Reconstitute in bacteriostatic water or sterile water. Gently swirl – do not shake. After reconstitution, aliquot immediately and store at -20°C (-4°F) to prevent degradation from freeze-thaw cycles.

8. Q: What is the recommended dosage for in vitro research?
A: For cell culture studies, typical concentrations range from 10-1000 nM. Start at 100 nM and optimize based on your specific cell type (e.g., B16-F10 melanoma cells, normal human melanocytes).

9. Q: Does MT1 have any effects on appetite or libido?
A: No. MT1 is MC1R-selective and does not significantly activate MC4R (which regulates appetite) or cross the blood-brain barrier. This is a key advantage over MT2 for research focused specifically on pigmentation and photoprotection.

10. Q: How should I store unopened MT1 vials?
A: Store unopened lyophilized vials at -20°C (-4°F) for long-term storage (up to 12 months). Stable for up to 3 months at 4°C (refrigerated). Do not open vials until ready to reconstitute.

11. Q: Do you offer bulk pricing for institutions?
A: Yes. Visit buypurepeptideseu.com and contact our wholesale division. We supply bulk peptide supply Europe and wholesale research peptides EU for universities and laboratories. Bulk deals available for orders of 10+ vials.

12. Q: Is payment secure?
A: 100%. We use AES-256 encryption and accept secure cryptocurrencies and credit cards. Your privacy is our priority.

13. Q: How long does delivery take to Scandinavia?
A: To buy peptides Stockholmbuy peptides Oslobuy peptides Copenhagen, or buy peptides Helsinki, delivery takes 3-5 business days. Lyophilized vials are shipped with ice packs for stability.

14. Q: What if my package is seized by customs?
A: Because we label our products for laboratory use only and ship from within Europe (no cross-continental customs checks for EU->EU), seizure rates are near zero. We are a trusted peptide suppliers Europe network.

15. Q: Do you sell to the UK post-Brexit?
A: Yes. We ship to buy peptides United Kingdom, specifically London, Manchester, Birmingham, Glasgow, Edinburgh, Bristol, Liverpool, Leeds, Sheffield, and Newcastle via Royal Mail tracked.

 

The difference between a wasted research cycle and a breakthrough in pigmentation research is the quality of your reagents. Do not trust your melanocortin research to a peptide supplier in Bulgaria that lacks a COA. Do not risk buying Melanotan 1 in Spain from a reseller who cannot verify purity or selectivity.

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For research use only, human consumption or therapeutic use. Must be 18+ to purchase. All products are for laboratory research purposes only. By ordering, you confirm you are a qualified researcher. Melanotan 1 (MT1 / Afamelanotide) is for in vitro and authorized in vivo research only, specifically for studies involving MC1R signaling, melanogenesis, photoprotection, vitiligo, and erythropoietic protoporphyria (EPP).  .  .  .  .  .   .  .  . . . . . . . . . . . . . . . . . . . . . . .  . . . . . . . .